Tuesday, September 27, 2011

Syphilis









 What is Syphilis






Syphilis is a sexually transmitted infection (STI) caused by the spirochete Treponema pallidum. It is a complex disease with protean variations that can mimic many common infections or illnesses. HIV infection may alter the natural history and management of syphilis, causing a more rapid course of illness, higher risk of neurologic complications, and potentially greater risk of treatment failure with standard regimens. Because many individuals with syphilis have no symptoms, or have symptoms that subside without treatment, sexually active individuals at risk of syphilis should receive regular screening for syphilis, as well as for other STIs. Many clinicians strongly recommend routine syphilis testing every 3-6 months for patients at risk of syphilis.

Symptom

After becoming infected with syphilis, there is an incubation period between of 9 to 90 days (the average being around 21 days) before the first signs and symptoms of the disease appear. Each stage of syphilis has characteristic signs and symptoms but any particular sign or symptom may or may not be present.

Some people with syphilis don't have any signs of infection. In other people, the signs may be very mild. They might not even know they have it. But even if the signs of infection go away on their own, the germs are still alive. They can cause serious health problems many years later.

The first (primary) stage involves the formation of the chancre. At this stage, syphilis is highly contagious. The primary stage can last one to five weeks. The disease can be transmitted from any contact with one of the ulcers, which are teeming with spirochetes. If the ulcer is outside of the vagina or on the scrotum, the use of condoms may not help in preventing transmission. Likewise, if the ulcer is in the mouth, merely kissing the infected individual can spread syphilis. Even without treatment, the early infection resolves on its own in most women.

In men, the first sign of syphilis may be a sore on the penis. In women, the first sign may be a sore around or inside the vagina. One might not even notice the sore, because syphilis sores don't hurt. The sores go away after three to six weeks.

Twenty five percent of cases will proceed to the secondary stage of syphilis, which lasts four to six weeks. This phase can include hair loss; a sore throat; white patches in the nose, mouth, and vagina; fever; headaches; and a skin rash. There can be lesions on the genitals that look like genital warts, but are caused by spirochetes rather than the wart virus. These wart-like lesions, as well as the skin rash, are highly contagious. The rash can occur on the palms of the hands, and the infection can be transmitted by casual contact.

If syphilis is not treated early, it spreads from the sore into the bloodstream. When syphilis gets into blood, it can cause many problems. The most common sign is a rash. The rash may show up, often on the palms of the hands or the soles of the feet, from two weeks to two months after the sore appeared. Other signs of syphilis include fever, sore throat and swollen lymph glands.

The third (tertiary) stage is the final stage of the disease involves the brain and heart, and is usually no longer contagious. At this point, however, the infection can cause extensive damage to the internal organs and the brain, and can lead to death.

After many years, people with syphilis who don't get treatment may begin to have problems in their brain and spinal cord. Syphilis may damage the heart and other organs, too.

Prevention

To prevent getting syphilis, you must avoid contact with infected tissue (a group of cells) and body fluids of an infected person. However, syphilis is usually transmitted by people who have no sores that can be seen or rashes and who do not know they are infected.
If you aren't infected with syphilis and are sexually active, having mutually monogamous sex with an uninfected partner is the best way to prevent syphilis.

Using condoms properly and consistently during sex reduces your risk of getting syphilis.
Washing or douching after sex won't prevent syphilis.

Even if you have been treated for syphilis and cured, you can be re-infected by having sex with an infected partner.
The risk of a mother transmitting syphilis to her unborn baby during pregnancy declines with time but persists during latent syphilis. To prevent passing congenital syphilis to their unborn babies, all pregnant women should be tested for syphilis.

Treatment

Treatment for syphilis usually consists of a two-week course of intramuscular penicillin injections or, in some cases, antibiotic tablets or capsules. If the patient has had syphilis for less than a year then fewer doses will be needed. If the patient is allergic to any antibiotics, or if there is any possibility that they may be pregnant, then the doctor should be informed so that alternative medication can be prescribed. It is important that the full course of treatment is completed. If treatment is interrupted then it may be necessary to start again from the beginning.
The patient will be asked about their sexual partners as it is important they are informed and tested as soon as possible. It is strongly advised to avoid any oral, vaginal or anal sex whilst having treatment, especially if the patient is in the early infectious stages of syphilis. Contact with any sores or rashes carries a risk of syphilis transmission.
After the treatment is completed the patient will be asked to attend the clinic at regular intervals for blood tests to check that the syphilis has gone. 

Once a person has been treated and confirmed cleared of syphilis, any future blood tests (e.g. for immigration reasons) will still be positive, because the body retains antibodies against the bacteria. Doctors can give the person a certificate explaining that they have been treated and no longer have syphilis. 

Treatment is only capable of killing the syphilis bacteria and preventing further damage. It cannot repair damage already done to organs, or prevent re-infection if the person is exposed to the bacteria again.


 

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